| 书目名称 | Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles |
| 编辑 | Hyung Yoon |
| 视频video | |
| 概述 | Nominated as an outstanding PhD thesis by the University of Toronto, Ontario, Canada.Describes Pd-catalyzed domino reactions in a concise manner.Provides a general overview of C-H activation.Presents |
| 丛书名称 | Springer Theses |
| 图书封面 |  |
| 描述 | .This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon–carbon bonds in high atom- and step-economy. .In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. .Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, andhighlights its synthetic utility. . .Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C–H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also |
| 出版日期 | Book 2020 |
| 关键词 | Carboiodination; Domino Reaction; C-H Activation; Cyanation; Borylation; Pd-Catalyzed Spirocyclization; Ca |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-54077-7 |
| isbn_softcover | 978-3-030-54079-1 |
| isbn_ebook | 978-3-030-54077-7Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
| issn_series | 2190-5053 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 17:24:01
