书目名称 | PEGylated Protein Drugs: Basic Science and Clinical Applications |
编辑 | Francesco M. Veronese |
视频video | |
概述 | Vast information on PEG and PEG-conjugates collected in one book.Competent authorship from academia and industry assures comprehensive information.Includes supplementary material: |
丛书名称 | Milestones in Drug Therapy |
图书封面 |  |
描述 | .PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development. . |
出版日期 | Book 2009 |
关键词 | Nucleotide; PEG preparation; PEGylation technique; Pegfilgrastim; Protein conjugation; cancer; cancer ther |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-7643-8679-5 |
isbn_ebook | 978-3-7643-8679-5Series ISSN 2296-6056 Series E-ISSN 2296-6064 |
issn_series | 2296-6056 |
copyright | Birkhäuser Basel 2009 |