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Titlebook: Oxygen Transport to Tissue XXVI; Paul Okunieff,Jacqueline Williams,Yuhchyau Chen Conference proceedings 2005 The Editor(s) (if applicable)

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Microvascular Oxygenation and Oxidative Stress During Postischemic Reperfusion,usion, while the blood flow and capillary perfusion decrease. The early increased ROS production, in turn, may impair oxygen consumption by endothelial cells, thus further promoting activation of oxygen to ROS. This event is substantiated by the finding that treatment with SOD maintains ROS at norma
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Hypoxia, Tumor Endothelium, and Targets for Therapy, mature well-differentiated endothelial cells in culture, would be sufficient and satisfactory models for tumor endothelial cells. However, the current hypothesis is that angiogenesis occurring during malignant disease is abnormal, and that therapeutic targets identified by studying endothelial cell
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Genetic Oxygen Sensor,rescence in these cells, but the magnitude was much smaller than expected. In summary, GFP can be used as an . probe for hypoxia. In GFP-expressing transgenic animals, . imaging of anoxic loci with a submicron spatial resolution may be possible.
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Varied Response of Spontaneous Tumors to Antiangiogenic Agents,ile endostatin increased total vessel spacing, and hypoxia and celecoxib had no marked effects. These results reinforce the idea that pathophysiological changes in spontaneous tumors are in general reflective of response in transplanted tumors. Furthermore, although DC101 inhibited growth in roughly
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Non-Invasive Measurement of Tumor Oxygenation Using Embedded Microparticulate EPR Spin Probe,owth rate. The measurements indicated that the pO. of the tumor decreased exponentially with tumor growth (size) and reached hypoxia (< 4 mm Hg). EPR imaging was used to identify the distribution of the particles in the tumor. The data showed a heterogeneous distribution of the probe particles withi
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Variability of Cerebral Hemoglobin Concentration in Very Preterm Infants During the First 6 Hours oh weight, gestational age, blood glucose and transcutaneous carbon dioxide tension. The remaining 1.1 µmol/1 (7.8%) were unexplained..We conclude that NIRS, which allows continuous monitoring of cerebral oxygenation and metabolism even in the first hours of postnatal life, is a valid technique to me
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