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Titlebook: Oxygen Radicals in Biology and Medicine; Michael G. Simic,Karen A. Taylor,Clemens Sonntag Book 1988 Springer Science+Business Media New Yo

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发表于 2025-3-21 16:39:07 | 显示全部楼层 |阅读模式
书目名称Oxygen Radicals in Biology and Medicine
编辑Michael G. Simic,Karen A. Taylor,Clemens Sonntag
视频video
丛书名称Basic Life Sciences
图书封面Titlebook: Oxygen Radicals in Biology and Medicine;  Michael G. Simic,Karen A. Taylor,Clemens Sonntag Book 1988 Springer Science+Business Media New Yo
描述This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These a
出版日期Book 1988
关键词Oxidation; antioxidant; biology; chemistry; pharmacology
版次1
doihttps://doi.org/10.1007/978-1-4684-5568-7
isbn_softcover978-1-4684-5570-0
isbn_ebook978-1-4684-5568-7
copyrightSpringer Science+Business Media New York 1988
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发表于 2025-3-21 22:58:44 | 显示全部楼层
Introduction to Peroxidation and Antioxidation Mechanismsty of the process (oxygen is consumed by energy-releasing processes such as cellular respiration and evolved in energy-trapping processes such as photosynthesis), and (4) the easy distribution of oxygen due to its gaseous state and its solubility in biocomponents under normal conditions.
发表于 2025-3-22 02:17:57 | 显示全部楼层
The Redox Thermodynamics for Dioxygen Species (O2, O 2 - ·, HOO·, HOOH, and HOO-) and Monooxygen Spetivity values for pK.’ range from -8.8 for (H.O)ClO. to 30.4 for H.O. This means that the formal potential (E°’) for reaction 1 in acetonitrile (MeCN) is +1.75 V vs. NHE in the presence of 1M(H.O)ClO. and -0.56 V in the presence of IM (Bu.N)OH.
发表于 2025-3-22 06:16:58 | 显示全部楼层
Singlet Oxygen: Current Mechanistic Aspects of Photo-Oxidationecular oxygen. In this paper it is shown that the oxygen quenching of triplet states also can lead to radicals which are produced via a process which competes with singlet oxygen formation. In addition, current results concerning the mechanism of reaction of the latter species with organic/biological substrates will be discussed.
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发表于 2025-3-22 16:41:27 | 显示全部楼层
Electron Spin Resonance Investigations of Oxygen-Centered Free Radicals in Biological Systemsxygen-centered free radical from other free radicals. The greatest limitation on the direct detection of oxygen-centered free radicals, aside from their high reactivity, is their paramagnetic properties.
发表于 2025-3-22 18:30:43 | 显示全部楼层
Redox Properties of Oxy and Antioxidant Radicalsnds on the reactivities of its subcomponents with oxy radicals, and its ability to reverse or prevent the damaging consequences of oxy radical reactions. Antioxidants are an important part of the defense system. Mechanistic aspects of some well-known and some potential physiological antioxidants are discussed.
发表于 2025-3-22 22:51:48 | 显示全部楼层
at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxi
发表于 2025-3-23 03:28:49 | 显示全部楼层
Peroxy Radicals and Singlet Oxygen (1O2) from the Addition of Superoxide Ion (O 2 - ·) to CCl4, CF3C not exhibit any reactivity with the allyl hydrogens of 1,4-CHD. Hence, at millimolar concentrations this peroxy radical (the suspected cytotoxin from the aerobic activation of CCl.) does not exist long enough to react with allylic hydrogens. The biological hazard of CCl. may be due to the transient formation of Cl.COOOOCCl..
发表于 2025-3-23 07:44:19 | 显示全部楼层
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