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Titlebook: Oxidative Stress in Human Reproduction; Shedding Light on a Ashok Agarwal,Rakesh Sharma,Damayanthi Durairajana Book 2017 Springer Internat

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书目名称Oxidative Stress in Human Reproduction
副标题Shedding Light on a
编辑Ashok Agarwal,Rakesh Sharma,Damayanthi Durairajana
视频video
概述Includes supplementary material:
图书封面Titlebook: Oxidative Stress in Human Reproduction; Shedding Light on a  Ashok Agarwal,Rakesh Sharma,Damayanthi Durairajana Book 2017 Springer Internat
描述This book discusses the role of oxidative stress in the reproductive system. The book reviews endogenous sources, methods of determining its levels in body fluid/tissues, the physiological roles of ROS, as well as its negative effects on the human reproductive processes. Also discussed are multiple extrinsic factors that could induce oxidative stress in the reproductive system. This volume covers various clinical pathologies related to the reproductive system that arise from or produce oxidative stress, both in the male and female. The use of antioxidants as a therapeutic measure to keep ROS levels in check are highlighted, describing the outcome of various clinical studies involving antioxidant supplementation in infertile patients.Infertility is a global disease that affects 15-25% of all couples, and oxidative stress arising from a multitude of sources has been implicated as one of the major contributing factors to the decline in human fertility. As such, this bookprovides an up-to-date review on the significance of ROS in human reproduction.
出版日期Book 2017
关键词antioxidant therapy; fertility; human reproduction; infertility; oxidative stress; reactive oxygen specie
版次1
doihttps://doi.org/10.1007/978-3-319-48427-3
isbn_softcover978-3-319-83940-0
isbn_ebook978-3-319-48427-3
copyrightSpringer International Publishing AG 2017
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Methods to Measure Reactive Oxygen Species (ROS) and Total Antioxidant Capacity (TAC) in the Reprodroduct of ROS are stable and easy to measure. High levels of ROS and low amounts of total antioxidants result in oxidative stress. High ROS levels can damage lipids, proteins and DNA in the cell. Accurate measurement of ROS or their end products is therefore important. This chapter describes various
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Extrinsic Factors Inducing Oxidative Stress (OS) in Male and Female Reproductive Systems,gical amount [1]. Biological reactions and mitochondrial processes generate regular amounts of ROS. In the female reproductive system, ROS plays an essential role in signal transduction pathways and metabolic pathways in processes such as follicular development, oocyte maturation, ovulation, implant
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Pathological Roles of Oxidative Stress (OS) in Diseases Related to Female Reproductive System,d to overcome infertility, including assisted reproductive technology (ART). Although . fertilization (IVF) is still the most commonly used technique, the number of ART cycles involving intracytoplasmic sperm injection (ICSI) has markedly increased [2].
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Therapeutic Role of Antioxidants (AOX) in the Treatment of Infertility,ontinuous basis, either by endogenous sources (see Chap. .) or exogenous sources (see Chap. .). ROS are essential for many processes in the human body, including essential intracellular signaling pathways [2]. Notwithstanding, an elevation in ROS eventually leads to oxidative stress (OS), defined as
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,Compendium of Oxidative Stress-Related Research from Cleveland Clinic (1993–2016),that have helped in deepening our understanding of oxidative stress (OS) and its effects on human reproduction, particularly in the male. In this chapter, we will explore the findings of past research conducted by the Cleveland Clinic researchers to date, which spans from reactive oxygen species (RO
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