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Titlebook: Oxidative Stress in Heart Diseases; Sajal Chakraborti,Naranjan S Dhalla,Madhu Dikshit Book 2019 Springer Nature Singapore Pte Ltd. 2019 he

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书目名称Oxidative Stress in Heart Diseases
编辑Sajal Chakraborti,Naranjan S Dhalla,Madhu Dikshit
视频video
概述Offers comprehensive information on the role of free radicals in heart diseases.Serves as a valuable resource for identifying drug targets for cardiovascular diseases.Provides interesting facts, real
图书封面Titlebook: Oxidative Stress in Heart Diseases;  Sajal Chakraborti,Naranjan S Dhalla,Madhu Dikshit Book 2019 Springer Nature Singapore Pte Ltd. 2019 he
描述.This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent  studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling,  it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease..
出版日期Book 2019
关键词heart diseases; oxidant; cardiovascular disease; oxidative stress; antioxidant; redox signalling; free rad
版次1
doihttps://doi.org/10.1007/978-981-13-8273-4
isbn_softcover978-981-13-8275-8
isbn_ebook978-981-13-8273-4
copyrightSpringer Nature Singapore Pte Ltd. 2019
The information of publication is updating

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Oxidant Stress in Atherosclerosis: Oxidatively Modified LDL and LOX-1s in animal models. Many of the currently used drugs modulate atherosclerosis by their action on LOX-1 receptor. New molecules that modulate LOX-1 are currently under investigation. sLOX-1 is a potential biomarker in acute coronary injury and further studies needs to be done before it can be put to clinical use.
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Oxidative Stress and Cardiovascular Risk and Prevention in Children and Adolescents future as an early tool to predict risk of developing cardiometabolic and lifestyle-related diseases in childhood and adolescence and later in adulthood..This review aims to discuss available data on all these aspects, with particular emphasis on the relationship between cardiometabolic risk and oxidative stress in children and adolescents.
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Oxidative Stress and Modulation of Cardiac Kv1.5 Channel the fundamental cause of AF is not still understood, but modulation of Kv1.5 channel has been successfully proved to be one of the strategic therapeutic interventions. In this chapter, the current knowledge on the effects of oxidative stress in heart has been summarized along with the roles of ion channels and their modulation.
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The Role of Redox Signalling in Cardiovascular Regenerationon of these two approaches. Unravelling these molecular and cellular signalling pathways is paramount to unlocking the potential of cardiac regenerative therapies, and theoretically revolutionising the medical management of patients with heart failure..In this chapter, we will review the role of oxi
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Molecular Targets and Novel Therapeutics to Target Oxidative Stress in Cardiovascular Diseasesress, however, there is a need to obviate or lessen the further tissue damage created by free radicals in later stages of CVD. However, apart from antioxidants, there are several potential candidates that may serve as therapeutic agents to curb oxidative stress in CVDs such as γ-glutamylcysteine sup
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Dietary Antioxidants in Mitigating Oxidative Stress in Cardiovascular Diseasesas therapeutics. Antioxidants target apoptosis, nitric oxide signaling, phosphatidylinositol signaling, protein kinase C to maintain redox homeostasis and prevent the risk of cardiovascular diseases. In this chapter, we have provided detailed description of biochemical and biological role of differe
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