Titlebook: Oxidative Stress and Toxicity in Reproductive Biology and Medicine; A Comprehensive Upda Kavindra Kumar Kesari,Shubhadeep Roychoudhury Book

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Molecular Interactions Associated with Oxidative Stress-Mediated Male Infertility: Sperm and Seminaogical aspects of sperm function such as motility and progression, hyperactivation, capacitation, acrosome reaction and zona-pellucida penetration prior to fertilization. In recent times, high-throughput proteomic platforms are used to identify the proteins associated with these aspects of sperm fun

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Unraveling the Molecular Impact of Sperm DNA Damage on Human Reproduction,alysis of sperm chromatin integrity and DNA damage as markers of semen quality. This is of particular interest, as preserving the genetic information is essential to achieve a successful reproductive event. Moreover, the presence of unrepaired DNA lesions can affect cellular functions, resulting in

LAIR

Role of Infection and Leukocytes in Male Infertility, contributing up to 35% of all cases. Mostly triggered by sexually transmitted diseases and uropathogens, chronic manifestation of such infection may cause irreversible infertility in the male. Male urogenital infection involves bacterial, viral, protozoal, and fungal infections many of which remain

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Bacteriospermia and Male Infertility: Role of Oxidative Stress, has been estimated that approximately 15% of all infertility cases are due to infections caused by uropathogens and in most of the cases bacteria are involved in infection and inflammation leading to the development of bacteriospermia. In response to bacterial load, excess infiltration of leukocyte

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Oxidant-Sensitive Inflammatory Pathways and Male Reproductive Functions,ying cause of infertility. In around 40–50% of male infertility cases, oxidative stress (OS)-related processes have been found to be responsible for fertility impairment. Inflammation is a major stress signal leading to OS. Redox imbalance occurs when endogenous antioxidant network fails to curb the

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Oxidative Stress and Varicocele-Associated Male Infertility,dative stress (OS) is proposed to be the mediator in how varicocele may negatively impact fertility. The imbalance of reactive oxygen species (ROS) and seminal antioxidants results in damage to sperm DNA and lipid membrane. There is evidence demonstrating higher OS level in men with varicocele which

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Metabolic Dysregulation and Sperm Motility in Male Infertility, considered as the cause of infertility in males which is most common. Even though energy metabolism is considered the main reason for the etiology of asthenospermia, few attempts are made to determine the pathway of its metabolic potential. Recognition of cellular as well as molecular pathways that

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Tale of Viruses in Male Infertility,ly 9% of the couple have fertility issues where the contribution of the male partner was estimated to be 50%. There are several factors that can amalgamate to give rise to male infertility. Among them are lifestyle factors, genetic factors and as well as several environmental factors. The causes of