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Titlebook: Ovarian Cancer Biomarkers; Mapping to Improve O Khalid El Bairi Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive

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书目名称Ovarian Cancer Biomarkers
副标题Mapping to Improve O
编辑Khalid El Bairi
视频video
概述Summarizes the etiology and pathogenesis of ovarian cancer.Highlights the implications of prognostic and diagnostic markers for precision medicine.Reviews the role of deep molecular and cellular profi
图书封面Titlebook: Ovarian Cancer Biomarkers; Mapping to Improve O Khalid El Bairi Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive
描述This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the treatment of ovarian cancer. It explores the use of genome-wide association analysis to identify genetic variants for the evaluation of ovarian carcinoma risk and prognostic prediction. Lastly, it highlights various diagnostic and prognostic ovarian cancer biomarkers for the development of molecular-targeted therapy.
出版日期Book 2021
关键词Ovarian Cancer; Biomarkers; Therapy Response; Prognosis; Liquid Biopsy
版次1
doihttps://doi.org/10.1007/978-981-16-1873-4
isbn_softcover978-981-16-1875-8
isbn_ebook978-981-16-1873-4
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive licence to Springer Nature Singapor
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Book 2021ling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmark
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Genetic Alterations in Ovarian Cancer as Prognostic and Predictive Biomarkers of Therapy Response a of the solid cancers that have benefited from genetic biomarkers for the implementation of targeted agents such as PARP inhibitors in clinical practice. This progress is discussed in this chapter based on recent studies and clinical trials.
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Cutting-Edge Technologies for Ovarian Cancer: An Overview of the Impact of Genetic Testing, Next-Gepact on patients’ outcomes according to the latest research findings. We finally depict the potential of single-cell sequencing in understanding OC heterogeneity based on recent proof-of-concept studies.
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The Hallmarks of Ovarian Cancer: Actionable Genetics, Targetable Pathways, and Predictive Biomarkerinatorial approaches. In this chapter, the clinical impact of genetics, biomarkers, and therapy in OC is reviewed based on the hallmarks of cancer. We particularly present a special emphasis on druggable targets investigated in phase II/III clinical trials for OC.
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