Titlebook: Organ Crosstalk in Acute Kidney Injury; Basic Concepts and C Carlos Guido Musso,Adrian Covic Book 2023 The Editor(s) (if applicable) and Th

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Genetic, Epigenetics, and Cell Adhesion in Acute Kidney Injury, tissue microenvironment that through complex interactions can trigger and perpetuate AKI. In this section, the experimental and clinical evidence implicating genetic, epigenetic mechanisms and phenotypic characteristics that contribute to the emergence of AKI will be presented.

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,Kidney–Muscle Crosstalk in Acute Kidney Injury,Muscle-kidney crosstalk in acute kidney injury represents a bidirectional axis which includes rhabdomyolysis with its characteristic leakage of nephrotoxic intracellular compounds, as well as the deleterious effects of acute kidney injury on muscle structure and metabolism.

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Carlos Guido Musso,Adrian CovicDiscusses a relevant topic in current Nephrology.Presents a new approach to acute kidney injury through the organ crosstalk perspective.Intends to improve therapeutic goal in acute kidney injury

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Acute Kidney Injury and Organ Crosstalk in COVID-19,m. As for the kidney alterations, they vary depending on the specific type of reported renal affectation, including proteinuria, hematuria, acute kidney injury, and its combination. COVID-19 induced cytokines storm is a paradigmatic example of pathogenic crosstalk among different body organs, particularly between the lung and the kidneys.