Titlebook: Oral Mucosa in Health and Disease; A Concise Handbook Lesley Ann Bergmeier Book 2018 Springer International Publishing AG 2018 Oral Microbi

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Oral Cancer: Recent Developments and Future Challenges,a and carcinoma in situ. Normal keratinocytes like many diploid human cells have a limited replicative capacity that is determined in part by the shortening of the DNA repeat sequences at the end of the chromosomes (telomeres) in the absence of the enzyme that maintains them (telomerase). Also, othe

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Epigenetics in the Oral Cavity,ated proteins, leading to remodeling of the chromatin and activation or inactivation of a gene. Changes in the epigenome contribute to the development and maintenance of cancer and autoimmune or inflammatory diseases. Epigenetic modifications are considered reversible and have therefore been present

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Clinical Management of Oral Mucosal Disease: A Literature Review,Many oral mucosal diseases exhibit an element of immune dysregulation and are frequently initiated by inflammatory processes that are either uncontrolled or unresolved..The purpose of this chapter is to outline the types of regimes that are used to manage these diseases and to indicate treatment dec

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Anchoring Junctions in the Oral Mucosa: Adherens Junctions and Desmosomes,brane proteins are coupled to cytoskeleton via a collection of adaptor proteins. The importance of each group of junctions, their constitutive proteins, tissue expression as well as the associated diseases are discussed in this chapter.

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Saliva and Gingival Crevicular Fluid: Contributions to Mucosal Defense,ecting from the most appropriate side of the tooth, etc. will make a difference as to the quantity and quality of biomarkers. Likewise, for saliva knowing its mechanisms of secretion will greatly aid the researcher and clinician in understanding the value of each biomarker.