Titlebook: Optimizing Breast Cancer Management; William J. Gradishar Book 2018 Springer International Publishing AG 2018 Anti - HER2 Therapy.Bisphosp

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Readdressing the Role of Surgery of the Primary Tumor in de Novo Stage IV Breast Cancer,rable metastatic disease enjoy long-term survival with systemic therapy. In patients with distant disease, the primary tumor in the breast has not classically been though to merit specific locoregional therapy. However, about 6% of Stage IV patients in the USA and up to 20% in limited resource envir

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Bureaucracy

Multi-gene Panel Testing in Breast Cancer Management,es encoding for proteins participating in DNA repair through homologous recombination (. and .). With the advent of massive parallel next-generation DNA sequencing, simultaneous analysis of multiple genes with a short turnaround time and at a low cost has become possible. The clinical validity and u

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Advances in Endocrine Therapy for Postmenopausal Metastatic Breast Cancer,preferred first-line therapy for patients with advanced estrogen receptor (ER) positive, HER2-negative breast cancer who do not have symptomatic visceral disease. Endocrine therapy is often continued in the second- and third-line setting, with chemotherapy deferred until tumor becomes endocrine ther

Addictive

Immune Checkpoint Blockade for Breast Cancer,eneration of activated tumor-directed T cells, infiltration of activated T cells into the tumor microenvironment, and killing of tumor cells by activated T cells. Tumor immune evasion can occur as a result of the disruption of each of these three key T cell activities, resulting in three distinct ca

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Sexual Function Post-Breast Cancer,on libido, sexual arousal, orgasmic function and the ability to have pleasurable intercourse. Evaluation and treatment of female sexual dysfunction is a significant unmet need in the breast cancer survivor in spite of the availability of safe and effective treatments.

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ikabteilung der Kölner Musikhochschule, zugleich Musikdirektor in Remscheid und seit 1928 auch Mitarbeiter am Westdeutschen Rundfunk; 1934/39 Direktor der Weimarer →Musikhochschule, gleichzeitig Dirigent der Weimarhallen-Konzerte der Staatskapelle und Leiter des Hochschulchors; 1939/45 Direktor der

endoscopy

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Rena Shah,Ruth M. O’Reganfordert eher zum Nachdenken auf. Nach einem Vierteljahrhundert Nachkriegsgeschichte haben sich aus der Erbmasse des ehemaligen Deutschen Reiches zwei eigenständige Staaten und Gesellschaftssysteme entwickelt. Sie haben sich zwar — aufgrund wesentlich von der Bundesrepublik getragener politischer Ans