书目名称 | Optimized Response-Adaptive Clinical Trials |
副标题 | Sequential Treatment |
编辑 | Thomas Ondra |
视频video | http://file.papertrans.cn/704/703338/703338.mp4 |
概述 | Publication in the field of natural sciences.Includes supplementary material: |
丛书名称 | BestMasters |
图书封面 |  |
描述 | Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences. |
出版日期 | Book 2015 |
关键词 | Allocation Sequence; Backward Induction; Clinical Trial Designs; Policy Iteration; Value Iteration |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-658-08344-1 |
isbn_softcover | 978-3-658-08343-4 |
isbn_ebook | 978-3-658-08344-1Series ISSN 2625-3577 Series E-ISSN 2625-3615 |
issn_series | 2625-3577 |
copyright | Springer Fachmedien Wiesbaden 2015 |