Titlebook: Optimization of Aerosol Drug Delivery; Leon Gradoń,Jan Marijnissen Conference proceedings 2003 Springer Science+Business Media Dordrecht 2

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Recent Advances in Drug Delivery Via Pressured Metered-Dose Inhalers, day, it remains the most commonly prescribed device for inhaled asthma medications, with world-wide production exceeding 500 million devices (Tansey, 1997a). The size of these canisters will vary, but assuming that they contain on average 120 doses, this equates to 2000 doses of medication taken ev

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Pulmonary Deposition and Effects of Aerosolized Drugs in Pulmonary Patients,pulmonary patients and to determine their exact place in the treatment of pulmonary disorders. This body of literature has been recently summarized in a number of consensus documents on the management of asthma and chronic obstructive pulmonary disease (COPD), the two most prominent pulmonary disord

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Targetting Aerosols to Disease Areas,oth reliable and practical. The use of MDI’s resulted in a decreased need for systemically administered bronchodilators or other anti-asthma drugs. This meant a considerable reduction of side-effects and an improvement of the quality of therapy.. The growing experience with MDI’s revealed some drawb

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Understanding the Mechanisms of Local Pulmonary Drug Absorption and Metabolism: An in Vitro Model o, of course, is not limited to supporting and supplementing the tissues of gas-exchange (leafs and alveoli, respectively); the conducting airways are also “more than just a barrier”, as recently stated by Folkerts and Nijkamp [2]. With every breath, the airway epithelium is exposed to the environmen