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Titlebook: Optimal Use of Sandimmun in Endogenous Uveitis; D. BenEzra,R. B. Nussenblatt,P. Timonen Conference proceedings 1988Latest edition Sandoz L

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书目名称Optimal Use of Sandimmun in Endogenous Uveitis
编辑D. BenEzra,R. B. Nussenblatt,P. Timonen
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图书封面Titlebook: Optimal Use of Sandimmun in Endogenous Uveitis;  D. BenEzra,R. B. Nussenblatt,P. Timonen Conference proceedings 1988Latest edition Sandoz L
描述Due to the largely disappointing therapeutic and sight­ Ensuing from the above observations, the following guidelines are suggested: saving results achieved so far with conventional therapy using systemic corticosteroids and cytotoxic agents, new treatment modalities have been sought. a) Start treatment with Sandimmun at initial doses of During the last four years, a total of over 300 patients 5 mg/kg/day. b) Use Sandimmun in combination with low dose sys­ suffering from endogenous intermediate and posterior temic corticosteroids if necessary, in order to uveitis, including more than 150 with Beh~et‘s disease achieve remission. involving the posterior segment of the eye, were treated with Sandimmun. The initial dose ranged from 5 to c) Use Sandimmun doses higher than 5 mg/kg/day on­ 10 mg/kg/day. These patients were treated openly with ly when absolutely indicated. Sandimmun in 11 independent studies all over the d) Taper Sandimmun dose as rapidly as possible to a world (over 200 patients) and in a masked manner in 4 maintenance dose below 5 mg/kg/day. e) Do not discontinue treatment with Sandimmun rap­ independent controlled studies (over 100 patients re­ idly.
出版日期Conference proceedings 1988Latest edition
关键词management; pathophysiology; physiology; safety; treatment; uveitis
版次1
doihttps://doi.org/10.1007/978-3-642-83368-7
isbn_ebook978-3-642-83368-7
copyrightSandoz Ltd, Basle / Springer-Verlag, Berlin Heidelberg 1988
The information of publication is updating

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Treatment of Endogenous Uveitis,nisolone 1.0%, fluometholone 0.1%) 4 to 10 times daily. Corticosteroid eye ointment at night time is added according to the severity of the ocular reaction. If constriction of the pupil with the formation of posterior synechiae is observed, strong short-acting mydriatics — cycloplegics (scopolamine
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Present Experience with Sandimmun,d posterior uveitis. In 11 studies from Europe, the U.S., Japan, Africa and Asia, over 200 patients suffering from endogenous uveitis refractory to treatment with steroids and cytotoxic drugs have been treated openly with Sandimmun. In 4 controlled masked studies from Israel, Japan, the U.S. and the
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Patient Selection for Sandimmun Treatment,From the accumulating experience with the use of Sandimmun, the following two groups of patients are appropriate candidates for treatment:
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References,Due to the largely disappointing therapeutic and sightsaving results achieved so far with conventional therapy using systemic corticosteroids and cytotoxic agents, new treatment modalities have been sought.
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