书目名称 | Optical Imaging of Cancer |
副标题 | Clinical Application |
编辑 | Eben Rosenthal,Kurt R.‘Zinn |
视频video | |
概述 | Covers a wide array of areas including optical imaging principles and potential clinical applications.Includes supplementary material: |
图书封面 |  |
描述 | .To describe principles of optical imaging including chemistry and physics of fluorescence, limitations/advantages of optical imaging compared to metabolic and anatomic imaging...Describe hardware adapted for small animal imaging and for clinical applications: endoscopes and operative microscopes...Outline FDA approved and newer optical imaging probes. Include discussion of chemistry and linkage to other proteins. Review current techniques to image cancer and the development of techniques to specifically image cancer cells...Review use of exploiting differences in tissue autofluorescence to diagnose and treat cancer. Include agents such as 5-aminoleculinic acid...Review mechanisms that require proteolytic processing within the tumor to become active fluorophores...Review use of cancer selective proteins to localize probes to cancer cells: include toxins, antibodies, and minibodies...Introduction of plasmids, viruses or other genetic material may be used to express fluorescent agents in vivo. This chapter will review multiple vectors and delivery mechanisms of optical imaging cassettes.Preclinical investigations into the use of optical contrast agents for the detection of primary tu |
出版日期 | Book 2010 |
关键词 | Antigen; Staging; Tumor; diagnosis; endoscopy; imaging techniques; optical coherence tomography; surgery |
版次 | 1 |
doi | https://doi.org/10.1007/978-0-387-93874-5 |
isbn_softcover | 978-1-4939-3932-9 |
isbn_ebook | 978-0-387-93874-5 |
copyright | Springer-Verlag New York 2010 |