| 书目名称 | Opioids | | 副标题 | Pharmacology, Abuse, | | 编辑 | Silvia L. Cruz | | 视频video | | | 概述 | Presents state-of-the-art guidelines on these complex and challenging pharmacologic agents.Provides a practical understanding of how opioids act and how to handle them safely and effectively.Discusses | | 图书封面 |  | | 描述 | .Opioids are responsible for the vast majority of preventable deaths related to drug use, and opioid crisis is a serious international health problem. Opioids are also the mainstay in pain treatment and are invaluable tools in palliative care. The purpose of this book is to present an overview of the complex field of opioid pharmacology through evidence-based chapters in clear language backed up with sound scientific evidence, providing researchers and health professionals with a firm understanding of their effects and mechanisms of action. The authors present an overview of the history of opioids from ancient civilizations to the current opioid crisis, covering state-of-the-art advances on opioid-induced signal transduction, opioids in pain management, and the neuroinflammatory effects of opioids. Also discussed are opioid use disorders and their treatment. The authors also review the growing body of evidence of opioid effects on innate and adaptive immune responses, discussing the molecules involved in the crosstalk between opioids and innate immunity receptors to provide an updated view of those compounds as important regulators of inflammation and host defense against pathoge | | 出版日期 | Book 2022 | | 关键词 | Opioids; heroin; fentanyl; opioid peptide; opiod receptors subtypes; TLR4 receptors; neuroinflammation; inn | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-031-09936-6 | | isbn_softcover | 978-3-031-09938-0 | | isbn_ebook | 978-3-031-09936-6 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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发表于 2025-3-21 19:26:59
