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Titlebook: Oncology in the Precision Medicine Era; Value-Based Medicine Ravi Salgia Book 2020 Springer Nature Switzerland AG 2020 oncology.cancer.prec

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Prostate Cancer,re paradigm can benefit from precision medicine. There is clearly a need to confidently avoid treatment for cancers that are slow growing, provide the optimal treatment to eliminate cancer primarily, and control aggressive disease using personalized treatment goals and regimens. We are moving beyond
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Molecular Testing in Ovarian Cancer: Recommendations and Treatment Considerations, frequent), endometrioid, and clear cell, mucinous, and low-grade serous carcinomas. Mutations in the tumor suppressor gene TP53, BRCA mutations, and abnormalities of DNA repair genes are found primarily in high-grade serous carcinomas, while mutations in other key molecular pathways such as Ras/Raf
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Genomic Cancer Risk Assessment, precision therapy. In this chapter we review the historical context and foundational science of cancer genetics and genomics and describe current approaches and challenges to the translation of genomic information for the practice of precision medicine and prevention. Known hereditary cancer syndro
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Triple-Negative Breast Cancer,r (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER-2). The annual incidence of TNBC is estimated to be approximately 40,000, with 20,000 diagnosed with metastatic disease in the USA (Plasilova et al. Medicine 95:e4614, 2016). The current standard-of-care treatment
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Digital Patient Engagement and Social Media,e, social media use is boundless, with ever-increasing capabilities and innovations. Popularity of social media use in the general public has increased tremendously. At the same time, there is a parallel increase in social media use by healthcare professionals and healthcare professional organizatio
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Primary Central Nervous System Tumors,nostication, and therapeutic management of primary central nervous system (CNS) tumors. An overview is provided of the major categories of primary CNS tumors and the key tumor subtypes which comprise these categories. With regard to diagnosis, the radiographic and pathologic features are highlighted
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