Titlebook: Oncogenes and Growth Control; Patricia Kahn,Thomas Graf Book 1986 Springer-Verlag Berlin Heidelberg 1986 ATP.Activation.Colon.DNA.Interleu

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Tissue-Specific Expression and Possible Functions of pp60, arried out, and the results promise to shed new light on the regulation of cell growth and differentiation. In the present review, I discuss the significance of these findings for a functional role of the c-. gene product.

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Book 1986n of research aimed at resolving these questions. It is organized into four sections, each containing a series of short reviews written by experts in the field. The general headings are: growth factors, receptors, and related oncogenes: transduction of mitogenic signals and .ras. oncogenes; nuclear

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Introduction years was the demonstration of something which was believed by many, but for a long time remained speculative: that these two groups of genes are in fact largely one and the same. This realization has been tremendously catalytic for both areas of research, and is the central concept around which this book is organized.

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Role of PDGF-Like Growth Factors in Autocrine Stimulation of Growth of Normal and Transformed Cells supported by recent experimental data, is that transformed cells may produce growth factors that stimulate their own growth in an autocrine manner. This review focuses on platelet-derived growth factor (PDGF) and related factors and their possible role in autocrine and paracrine mechanisms in both normal and transformed cells.

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mosar, although . is grouped with the tyrosine kinase oncogenes, its structural and functional peculiarities have set it apart from other members of this group and have hampered attempts to understand its normal role and mechanism of action.

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