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Titlebook: On the Study and Practice of Intravenous Anaesthesia; Jaap Vuyk,Frank Engbers,Sandra Groen-Mulder Book 2000 Springer Science+Business Medi

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The Effect of Opioids on the Pharmacokinetics and Pharmacodynamics of Propofolofol and the various opioids fentanyl, alfentanil, sufentanil, and remifentanil considerable progress has been made in the characterisation of the pharmacokinetics and pharmacodynamics of these agents and of the combinations thereof.
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Strategies to Prevent Awareness and the clinical effect can be considered instead. Based on this concentration-effect relationship, it is possible to select a target plasma concentration. This target concentration can be defined as the plasma concentration which, on the basis of available information, is most likely to yield the
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Patient Controlled Sedation During Locoregional Anaesthesiathe procedure. Increasingly, procedures which were once undertaken as open surgical operations can now be achieved by less invasive techniques. Many procedures that required general anaesthesia in the past can now be performed under locoregional anaesthesia and sedation. This has led to an increase
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