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Titlebook: OPLL; Ossification of the Kazuo Yonenobu (Vice-Director),Kozo Nakamura (Prof Book 20062nd edition Springer-Verlag Tokyo 2006 Myelopathy.bo

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75 the Investigation Committee for OPLL, under the auspices of the Japanese Ministry of Health and Welfare, established diagnostic criteria for the condition, and with growing awareness of OPLL among Japanese researchers and spinal surgeons, the number of patients diagnosed with the condition in Jap
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Book 20062nd editionestigation Committee for OPLL, under the auspices of the Japanese Ministry of Health and Welfare, established diagnostic criteria for the condition, and with growing awareness of OPLL among Japanese researchers and spinal surgeons, the number of patients diagnosed with the condition in Japan has inc
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Pathology of Ossification of the Ligamentum Flavumip of the nodule-shaped ossification. Ossification extended along the superficial layer of the hypertrophied ligament, as in OPLL. It was suggested that the mechanism of OLF development depends intimately not only on dynamic and static mechanical stresses but also on the role of some growth factors as well.
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Genetic Susceptibility to OPLLJapanese is needed to investigate etiological identity or differences in distinct populations. Understanding the role of genetic factors in the etiology of OPLL allows more precise definition of nongenetic factors, such as environmental and lifestyle- oriented factors, which may help improve the patients’ status.
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