| 书目名称 | Nuclear-Cytoplasmic Transport |
| 编辑 | Weidong Yang |
| 视频video | |
| 概述 | Contains recent findings of nuclear-cytoplasmic transport systems through the nuclear envelope (NE) of eukaryotic cells.Describes structure and role of nuclear pore complexes (NPCs) in trafficking mac |
| 丛书名称 | Nucleic Acids and Molecular Biology |
| 图书封面 |  |
| 描述 | Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.. |
| 出版日期 | Book 2018 |
| 关键词 | nuclear transport; nuclear pore complexes; nuclear envelope; nucleoporins; nuclear |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-77309-4 |
| isbn_softcover | 978-3-030-08425-7 |
| isbn_ebook | 978-3-319-77309-4Series ISSN 0933-1891 Series E-ISSN 1869-2486 |
| issn_series | 0933-1891 |
| copyright | Springer International Publishing AG, part of Springer Nature 2018 |
发表于 2025-3-21 18:27:35
