| 书目名称 | Nuclear Pore Complexes in Genome Organization, Function and Maintenance | | 编辑 | Maximiliano D’Angelo | | 视频video | | | 概述 | Clear description of the current knowledge in genome organization.Exposes new concepts of the roles of nuclear pore complexes in genomic organization and genome protection/maintenance.A unique source | | 图书封面 |  | | 描述 | The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical role in the establishment and maintenance of chromatin organization and in the regulation of gene activity. These findings, which oppose the traditional view of NPCs as channels with only one: the facilitation of nucleocytoplasmic molecule exchange, have completely transformed our understanding of these structures. This book describes our current knowledge of the role of NPCs in genome organization and gene expression regulation. It starts by providing an overview of the different compartments and structures of the nucleus and how they contribute to organizing the genome, then moves to examine the direct roles of NPCs and their components in gene expression regulation in different organisms, and ends by describing the function of nuclear pores in the infection and genome integration of HIV, in DNA repair and telomere maintenance, and in the regulation of chromosome segregation and mitosi | | 出版日期 | Book 2018 | | 关键词 | Genome Organisation; Genomic Stability; Nuclear Pore Complexes; Nuclear Transport; Nucleus; gene expressi | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-71614-5 | | isbn_softcover | 978-3-319-89088-3 | | isbn_ebook | 978-3-319-71614-5 | | copyright | Springer International Publishing AG 2018 |
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书目名称Nuclear Pore Complexes in Genome Organization, Function and Maintenance影响因子(影响力)
书目名称Nuclear Pore Complexes in Genome Organization, Function and Maintenance影响因子(影响力)学科排名
书目名称Nuclear Pore Complexes in Genome Organization, Function and Maintenance网络公开度
书目名称Nuclear Pore Complexes in Genome Organization, Function and Maintenance网络公开度学科排名
书目名称Nuclear Pore Complexes in Genome Organization, Function and Maintenance被引频次
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发表于 2025-3-21 17:43:26
