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Titlebook: Novel Synthetic Drugs in Migraine; Paolo Martelletti,Lars Edvinsson Book 2022 The Editor(s) (if applicable) and The Author(s), under exclu

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发表于 2025-3-21 17:37:18 | 显示全部楼层 |阅读模式
书目名称Novel Synthetic Drugs in Migraine
编辑Paolo Martelletti,Lars Edvinsson
视频video
概述First book on the novel synthetic treatment of migraine.Compares gepants with triptans or CGRP monoclonal antibodies.Compares ditans with triptans
丛书名称Headache
图书封面Titlebook: Novel Synthetic Drugs in Migraine;  Paolo Martelletti,Lars Edvinsson Book 2022 The Editor(s) (if applicable) and The Author(s), under exclu
描述.Published in the series Headache, endorsed by the European Headache Federation, this is the first book on the novel synthetic treatment of migraine with ditans (lasmiditan) and gepants (atogepant, ubrogepant, rimegepant, vazegepant). These drugs will provide additional options for people with migraine put at risk of side effects by other medications or with unsatisfactory response to previous drugs. There is now a sufficient amount of literature published to interest a wide multidisciplinary readership (general physicians, general neurologists, clinical psychologists, neurologists in training, and medical students) facing every day this burdensome disorder in their clinical practice. The book aims therefore at offering an overview of these new drugs for both acute and prophylactic treatments of migraine, covering studies on clinical evidence, tolerability, and the different stages of clinical development..
出版日期Book 2022
关键词acute treatment; preventive treatment; gepants; ditans; Pharmacological Targets
版次1
doihttps://doi.org/10.1007/978-3-030-95334-8
isbn_softcover978-3-030-95336-2
isbn_ebook978-3-030-95334-8Series ISSN 2197-652X Series E-ISSN 2197-6538
issn_series 2197-652X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Zavegepant,inical data are available regarding its therapeutic efficacy and safety profile. Data on metabolism, pharmacogenomics, and pharmacokinetics profile are limited, therefore new studies are needed to define its efficacy, safety, tolerability, and pharmacological interaction.
发表于 2025-3-22 20:13:32 | 显示全部楼层
Molecular Mechanisms of 5-HT1F Receptor Agonists,igraine. Updated evidence suggests that ditans exert their antimigraine effects by modulating the trigeminovascular system, while devoid of cardiovascular safety drawbacks shared by previous antimigraine drugs targeting 5-HT receptors, namely ergot-derivatives and triptans.
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Update on Old and Current Targets for Antimigraine Therapies,hese are effective with few side effects. In this chapter, we discuss mechanisms involved in the use of and treatment with the different medications and use their effectiveness to understand a bit more of the underlying biology of migraine.
发表于 2025-3-23 04:36:12 | 显示全部楼层
Book 2022ith ditans (lasmiditan) and gepants (atogepant, ubrogepant, rimegepant, vazegepant). These drugs will provide additional options for people with migraine put at risk of side effects by other medications or with unsatisfactory response to previous drugs. There is now a sufficient amount of literature
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