Titlebook: Novel Approaches to Treatment of Osteoporosis; R. Graham G. Russell,Timothy M. Skerry,Uwe Kollenk Conference proceedings 1998 Springer-Ver

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Mechanotransduction: An Inevitable Process for Skeletal Maintenance,ired Wolff to put forward his law of bone transformation, which can be paraphrased to state that trabecular trajectories align with the principal directions of mechanical stress and thus trabecular structures are optimized to their functional loads (Wolff 1892). In fact, trabecular patterns in bone

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The Regulation of Gene Expression in Bone by Mechanical Loading,g on the skeleton. Historical comments on the stronger skeletons of individuals with active lifestyles are attributed to Galileo, but serious studies of the relationships between bone mass and loading were not made until the late 1800s, when Culmann, von Meyer, Roux and Wolff initiated what has now

synchronous

Amplification of the Osteogenic Stimulus of Load-Bearing as a Logical Therapy for the Treatment andechanical loading and a normal loading history. There is a substantial literature documenting instances in which changes in loading history are reflected by changes in bone structure. There are also instances in which the normal structure:functional relationship is achieved but not maintained despit

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Ernst Schering Foundation Symposium Proceedingshttp://image.papertrans.cn/n/image/668354.jpg

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978-3-662-09009-1Springer-Verlag Berlin Heidelberg 1998