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Titlebook: Novel Antischizophrenia Treatments; Mark A. Geyer,Gerhard Gross Book 2012 Springer-Verlag Berlin Heidelberg 2012 Cognition.Neurotransmitte

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书目名称Novel Antischizophrenia Treatments
编辑Mark A. Geyer,Gerhard Gross
视频video
概述Provide up-to-date information on approaches to the discovery of treatments for cognitive deficits in schizophrenia.Provide information on promising new targets for therapeutics in the treatment of sc
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Novel Antischizophrenia Treatments;  Mark A. Geyer,Gerhard Gross Book 2012 Springer-Verlag Berlin Heidelberg 2012 Cognition.Neurotransmitte
描述This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
出版日期Book 2012
关键词Cognition; Neurotransmitters; Psychopharmacology; Schizophrenia
版次1
doihttps://doi.org/10.1007/978-3-642-25758-2
isbn_softcover978-3-642-43809-7
isbn_ebook978-3-642-25758-2Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 2012
The information of publication is updating

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Clinical Instruments to Evaluate and Guide Treatment in Schizophrenia,ces. This has led to the use of functional capacity measures which monitor an individual’s ability to perform functionally meaningful tasks even if they do not complete these tasks. Attention has also focused on interview-based measures of cognition and negative symptoms. Both of these psychopatholo
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Towards Medication-Enhancement of Cognitive Interventions in Schizophrenia, might be possible to significantly enhance the efficacy of cognitive therapies. We review and suggest several laboratory measures that might detect potential pro-neurocognitive effects of drugs in individual patients, using a “test dose” design, aided by specific biomarkers predicting an individual
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Mutant Mouse Models in Evaluating Novel Approaches to Antipsychotic Treatment,enetics of schizophrenia and mutant models relating to replicable risk genes. Lastly, we extend this discussion by exemplifying two new variant approaches in mutant mice that may serve as prototypes for advancing antipsychotic drug development. There is continuing need not only to address numerous t
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The Role of Dopamine D3 Receptors in Antipsychotic Activity and Cognitive Functions,iating positive symptoms is still unsettled, selective D. receptor antagonism has therapeutic features for schizophrenia and beyond as demonstrated by several animal models: improved cognitive function, emotional processing, executive function, flexibility, and social behavior. D. receptor antagonis
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