Titlebook: Nonselective Cation Channels; Pharmacology, Physio Detlef Siemen,Jürgen Hescheler Book 1993 Birkhäuser Verlag 1993 GABA.biophysics.muscle.p

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Nonselective Cation Channels: Physiological and Pharmacological Modulations of Channel Activity membrane and — in most cases -to an increase in the intracellular Ca. concentration. Nonselective cation channels presumably form a large family of diverse channels which are modulated by various extracellular and intracellular signals. Structure and regulation of ligand-operated and cyclic nucleot

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AMPA-Type Glutamate Receptors — Nonselective Cation Channels Mediating Fast Excitatory Transmission ogress was mainly achieved by technical advances, among them the patch-clamp technique in brain slices (Edwards et al., 1989), fast application of agonists (Franke et al., 1987), and cloning and functional expression of GluR channels of the nonNMDA type (e.g., Hollmann et al., 1989)..A suitable mode

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Mechanically Sensitive, Nonselective Cation Channelsnsducers for forces derived from osmotic or hydraulic gradients and shear stress. They may also be modulated by membrane voltage and various ligands. MSCs are most commonly cation selective, passing calcium as well as monovalent ions, but some are K. selective, and a few are anion selective. MSCs oc

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Mechanosensitive Nonselective Cation Channels in the Antiluminal Membrane of Cerebral Capillaries (Bd not distinguish between K. and Na. ions and were also permeable to Ca. and Ba. ions. With monovalent cations in the patch pipette the single-channel conductance was 37 pS and with the divalent cations Ba. and Ca. slope conductance was 16 and 19 pS, respectively. The open probability of the SA-chan

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Cyclic AMP-Gated Cation Channels of Olfactory Receptor Neuronson of a nonselective cation channel. Single-channel recordings from extraciliary regions of isolated salamander olfactory receptor neurons have greatly improved our knowledge about distinctive properties of the cAMP-gated channel such as channel kinetics, modulation through divalent cations, and pha

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Renal Epithelial Cells Show Nonselective Cation Channel Activity and Express a Gene Related to the cputative physiological function. Renal epithelial nonselective cation channels may play a role in volume regulation, calcium entry, cell proliferation, and sodium reabsorption..In some renal epithelia cGMP seems to be involved in the regulation of nonselective cation channels. Furthermore, there is