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Titlebook: Nonlinearities, Disequilibria and Simulation; Proceedings of the A Kumaraswamy Velupillai (Associate Director) Conference proceedings 1992

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Kumaraswamy Velupillaid serine proteases (MASPs). When MBL recognizes foreign, e.g., the surface of some microorganisms, or altered host surfaces the MASPs are activated and this will in turn lead to the initiation of the complement system, i.e., activation of complement by the MBL pathway. This will end up in increased
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Poul Nørregaard Rasmussen,R. M. Goodwincognition subunit of this complex and its binding to the specific targets leads to the formation of active C1, which in turn activates the CCP in an immunoglobulin-dependent or -independent manner. C1q is a hexameric glycoprotein composed of 18 polypeptide chains of three different types (A, B, and
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ely. They are assembled into a Ca.-dependent C1s–C1r–C1r–C1s tetramer which in turn associates with the recognition protein C1q. The C1 complex circulates in serum as a zymogen and is activated upon binding of C1q to appropriate targets, such as antigen–antibody complexes. This property is used for
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Sven Danø,Lars-Gunnar Svensson,Rolf Färess in laboratory complement diagnosis. Although it is well documented that complement plays a decissive role in the pathogenesis of various diseases, it is somewhat surprising that achievements in complement research only find limited implementation in the clinic. Despite the presence of a broad spe
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ss in laboratory complement diagnosis. Although it is well documented that complement plays a decissive role in the pathogenesis of various diseases, it is somewhat surprising that achievements in complement research only find limited implementation in the clinic. Despite the presence of a broad spe
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