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Titlebook: Noninvasive Imaging of Cardiac Metabolism; Single Photon Scinti E. E. Wall Book 1987 Martinus Nijhoff Publishers, Dordrecht 1987 assessment

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书目名称Noninvasive Imaging of Cardiac Metabolism
副标题Single Photon Scinti
编辑E. E. Wall
视频video
丛书名称Developments in Cardiovascular Medicine
图书封面Titlebook: Noninvasive Imaging of Cardiac Metabolism; Single Photon Scinti E. E. Wall Book 1987 Martinus Nijhoff Publishers, Dordrecht 1987 assessment
描述F.J.Th. WACKERS Metabolic imaging: The future of cardiovascular nuclear imaging? Since cardiovascular nuclear imaging emerged as a new subspecialty in the mid-1970s, the field has gone through an explosive growth. Radionuclide techniques became readily recognized as important new diagnostic aids in the armamentarium of the clinical cardiologist. Initially, cardiovascular nuclear imaging focused on static myocardial imaging using either thallium-201 or technetium-99m-pyrophosphate for diagnosing acute myocardial infarction. Shortly thereafter, multigated equilibrium radionuclide angiocardiography became the most widely used noninvasive method for assessing cardiac function. Furthermore, attention and clinical application shifted towards the use of radionuclide techniques in conjunction with exercise testing, either with thallium-20 1 myocardial perfusion imaging or technetium-99m left ventricular function studies. The future of cardiovascular nuclear imaging appeared exciting and promising. However, around 1980 pessimists predicted the premature demise of cardiovascular nuclear imaging with the introduction of digital subtraction angiography and nuclear magnetic resonance imaging. T
出版日期Book 1987
关键词assessment; cardiology; cardiovascular; development; evaluation; fat; heart; imaging; magnetic resonance spe
版次1
doihttps://doi.org/10.1007/978-94-009-3287-6
isbn_softcover978-94-010-7976-1
isbn_ebook978-94-009-3287-6Series ISSN 0166-9842
issn_series 0166-9842
copyrightMartinus Nijhoff Publishers, Dordrecht 1987
The information of publication is updating

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Uptake and distribution of radioiodinated free fatty acids in the dog heart,ts in the search for a tracer to follow myocardial energy metabolism. When labeled with a gamma radiation emitting isotope, such substances may be observed with a gamma-camera and eventually their time course in the heart can be studied . and differences in metabolic behaviour between normal and pathological heart tissue may be noticed.
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Radioiodinated free fatty acids: a clue to myocardial metabolism?,esses have to be extremely flexible to respond accordingly. Also the different fuels, which are transported to the heart by the blood, vary in concentration, needing a fine tuned mechanism of combined stubstrate utilization.
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Assessment of glucose utilization in normal and ischemic myocardium with positron emission tomograp energy whereas the other two third arises from fatty acids. Later on, Randle .. [3] and Neely .. [4] showed that during myocardial ischemia, glucose becomes the preferential substrate of the myocardium that and anaerobic metabolism is mostly maintained by glycolysis.
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0166-9842 ecialty in the mid-1970s, the field has gone through an explosive growth. Radionuclide techniques became readily recognized as important new diagnostic aids in the armamentarium of the clinical cardiologist. Initially, cardiovascular nuclear imaging focused on static myocardial imaging using either
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Chain-modified radioiodinated fatty acids,lizes both odd and even numbered carbon chain lengths as well as both saturated and unsaturated fatty acids, the acids primarily metabolized are the 16-carbon saturated palmitic acid (x=14 in the formula below), the 18-carbon saturated stearic acid (x=16) and the 18-carbon unsaturated oleic acid (x=y=7).
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Iodinated free fatty acids: reappraisal of methodology,fe of 13.3 h and a low body exposure. Heptadecanoic acid labeled with I-123 (I-123-HDA) in the omega-position is structurally almost identical to the naturally occurring FFA [2] and will be the FFA of choice for the studies mentioned in this chapter.
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