| 书目名称 | Non-coding RNAs in Complex Diseases | | 副标题 | A Bioinformatics Per | | 编辑 | Xia Li,Juan Xu,Yunpeng Zhang | | 视频video | | | 概述 | Offers an in-depth and comprehensive review on current understanding of regulatory ncRNAs in complex diseases from the view of bioinformatics.Conveys state-of-the-art bioinformatics tools and methods | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | .This book offers an in-depth and comprehensive review on current understanding of regulatory ncRNAs in complex diseases from a view of bioinformatics. It conveys state-of-the-art bioinformatics tools and methods for ncRNAs from computational detection, functional prediction, to their roles in diseases. Computational methods used to investigate uncharacterised ncRNAs in diseases are mainly summarized in seven aspects: DNA variation of ncRNAs in diseases, prioritization of disease-related ncRNAs, dysregulation epigenetic factors that regulate ncRNA misexpression (DNA methylation and histone-modification), complex crosstalk across ncRNAs, ncRNAs acted as competing regulators to mediate the expression of protein-coding genes, non-coding RNAs mediated risk pathways,and their contributions to drug target predictions. The generally used data resources of ncRNAs are also listed in the end. This book provides important information on the current progress in the fast-moving fields of bioinformatics for regulatory ncRNAs. It provides a timely and useful reference for computational biologists, specifically with RNA interests, and other related areas..Prof. Xia Li is a Professor and the Dean o | | 出版日期 | Book 2018 | | 关键词 | RNA bioinformatics; lncRNA-disease associations; non-coding RNAs; ncRNA; genome-wide discovery; computati | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-13-0719-5 | | isbn_softcover | 978-981-13-4486-2 | | isbn_ebook | 978-981-13-0719-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | Springer Nature Singapore Pte Ltd. 2018 |
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发表于 2025-3-21 18:17:27
