书目名称 | Non-Myeloablative Allogeneic Transplantation |
编辑 | Asad Bashey,Edward D. Ball |
视频video | |
丛书名称 | Cancer Treatment and Research |
图书封面 |  |
描述 | Non-myeloablative allogeneic stem cell transplantation (also known as mini-transplantation or reduced-intensity conditioning transplantation) is a major advance in the field of hematopoietic transplantation within the last 5 years. This approach uses non-cytotoxic or reduced-intensity cytotoxic therapy to prepare patients for allografting of hematopoietic stem cells and lymphocytes. It has the potential to deliver the potent anti-tumor immunotherapy and bone marrow replacement capacity of allogeneic stem cell transplantation to patients with reduced treatment-related morbidity and mortality. It may also enable allogeneic transplantation in patients who would be considered ineligible for conventional transplants because of co-morbidity or advanced age. However, this approach may necessitate more careful monitoring of post-transplant chimerism and malignant disease-status than is usual with conventional allografting. There is also controversy regarding the best preparative regimen and graft-versus-host disease prophylaxis to use. |
出版日期 | Book 2002 |
关键词 | Immunosuppression; bone marrow; cell; hematopoietic stem cell; hematopoietic stem cell transplantation; i |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4615-0919-6 |
isbn_softcover | 978-1-4613-5304-1 |
isbn_ebook | 978-1-4615-0919-6Series ISSN 0927-3042 Series E-ISSN 2509-8497 |
issn_series | 0927-3042 |
copyright | Springer Science+Business Media New York 2002 |