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Titlebook: Nitric Oxide in Pulmonary Processes; Role in Physiology a Maria G. Belvisi,Jane A. Mitchell Book 2000 Springer Basel AG 2000 Respiratory re

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Non-Adrenergic Non-Cholinergic Neurotransmission in the Airways: Role of Nitric Oxide (NO)-containing nerves in the control of airway smooth muscle function. Neural control of airway smooth muscle is very complex since in addition to cholinergic and adrenergic innervation there is a non-adrenergic non-cholinergic (NANC) innervation. The existence of a NANC nervous system in the gast
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Nitric Oxide and Bronchial Hyperresponsivenessresent in exhaled air of animals and humans [., .]. The respiratory tract, nerves endothelial cells, vascular and airway smooth muscle cells, inflammatory cells (macrophages, neutrophils, mast cells) and the airway epithelium are sources for NO production [.]. The different effects of NO are mediate
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Role of Nitric Oxide in Airway Inflammationcleotide phosphate (NADPH), flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD) and tetrahydrobiopterin [., .]. Three genes encoding NO synthases are expressed as enzymes in mammals [., .]. These enzymes are denoted either by their historical order of cloning or by the cell type from whic
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Nitric Oxide in Exhaled Air: Relevance in Inflammatory Lung Diseasecontrol of airway function and in the pathophysiology of airway diseases [.–.]. All three isoforms of NO synthase (NOS) exist within the respiratory tract [.–.]. The endothelial constitutive isoform (eNOS) is localised to bronchial endothelial cells and to epithelial cells [.] and the neuronal isofo
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Luminal Nitric Oxide in the Upper Airways: Implications for Local and Distal Sites of Actionnose, but may not be vital for the human species. The well-known protective functions of the nose are heating, humidification and filtration of inhaled air. Recently, other protective and regulating functions pertaining to the nasal airways and the paranasal sinuses have been proposed, which involve
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