书目名称 | Nitric Oxide | 副标题 | Methods and Protocol | 编辑 | Helen O. McCarthy,Jonathan A. Coulter | 视频video | | 概述 | Addresses the challenges of accurate quantification of nitric oxide in either in vitro or in vivo models with practical, step-by-step protocols.Includes readily reproducible techniques crafted by lead | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | The past two decades have seen an explosion in the number of research articles relating to both the physiological and pathological responses evoked by nitric oxide generation. Despite this, accurate quantification of nitric oxide in either in vitro or in vivo models remains challenging, due to the relatively unstable nature of the molecule.In Nitric Oxide: Methods and Protocols, experts in the field provide a detailed reference manual packed with step-by-step approaches to reproduce various complex protocols within your own laboratory.Divided into two parts, the volume first covers various disparate protocols relating to the direct detection and quantification of nitric oxide, including techniques which detail how to image real time in vivo generation of nitric oxide, quantify nitric oxide production in the rat brain, and the detect ultralow levels of nitric oxide in the pM range, and the book then continues with a section on techniques designed to either inhibit or enhance nitric oxide, with an aim to achieve therapeutic gain, featuring the inhibition of the nitric oxide synthase enzymes using viral, shRNA delivery systems to prevent cardiovascular dysfunction, peripheral neuropat | 出版日期 | Book 2011 | 关键词 | Biofilms; Detection and quantification; In vivo generation; Nanoparticles; Nitrate; Physiological, patho | 版次 | 1 | doi | https://doi.org/10.1007/978-1-61737-964-2 | isbn_softcover | 978-1-4939-5791-0 | isbn_ebook | 978-1-61737-964-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC 2011 |
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