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Titlebook: New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM; Mahmood S. Mozaffari Book 2013 Springer Science+Business Media

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Correction of Diabetes-Induced Endothelial Progenitor Dysfunction to Promote Retinal Vascular Repaiight-­threatening macular edema, macular ischemia and ultimately preretinal neovascularization. Bone marrow derived endothelial progenitor cells (EPCs) play a critical role in vascular maintenance and repair. There is still great debate about the most appropriate markers that define an EPC and much
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Oxidative Stress and Apoptotic Biomarkers in Diabetic Retinopathy,ures of DR include leukocyte adhesion, increased vascular permeability, neovascularization and neuronal cell death. Early diagnosis and intervention are important to prevent or at least ameliorate the development of DR. Recent reports indicate that pathophysiological mechanisms leading to diabetic r
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The Role of Inflammatory Cytokines in Diabetic Nephropathy: Potential Use as Predictive Markers forypertension (systemic and/or intraglomerular) in diabetic nephropathy are well-­established. Importantly, increasing evidence indicates that activated innate immunity and inflammation are major players in pathogenesis of diabetic nephropathy. This notion is supported by the recent literature indicat
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Preventing Hyperglycemia and Tissue Injury in Diabetes: The Dynamic Role of 2,3 Indoleamine Dioxygent the occurrence of hyperglycemia and its deleterious effects in patients at risk. A major obstacle in achieving this important goal of the preventive medicine is represented by the heterogeneity of the disease as well as of the targeted organs..Recent clinical and experimental studies, however, ha
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An Integrative Approach to Chronic Wounds in Patients with Diabetes: PPPM in Action,tails, incorporating concepts of basic biomechanics and endurance limits. The key points are the interdependence of cell and the extracellular matrix (ECM): with the cells producing ECM and ECM affecting cell fate and behavior. This is followed by biochemical and cellular basis of pathogenesis of di
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Understanding Inflammation: The Key to Targeted Preventive Measures for Diabetes and Periodontitis,appears to contribute to the severity and degree of control of the other. Periodontal treatment that reduces gingival inflammation aids in the control of hyperglycemia. Periodontitis is accompanied by gingival bleeding and the production of an inflammatory exudate termed gingival crevicular fluid (G
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Cancer Predisposition in Diabetic Patients: Risk Assessment and Targeted Preventive Measures,c disorders. Increasing evidence indicates that diabetic patients are highly predisposed to a spectrum of oncologic diseases. Understanding of molecular pathomechanisms of the cancer-provocation in DM is of great importance for the properly organised diabetes care. This chapter focuses on the epidem
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Recognition of Individual Risks by Analysis of Subcellular Imaging Insights into Chromium Picolinats for.The ubiquitous agent is the chromium picolinate (CrPic) has become very popular for treating type 2 diabetics as well as obesity- and diabetes-predisposed individuals: it is reported that CrPic generates sales for more than 100 million dollars annually. The supplements by CrPic are freely avai
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