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Titlebook: New Rapid-acting Antidepressants; Kenji Hashimoto,Mario Manto Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive l

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发表于 2025-3-21 17:46:26 | 显示全部楼层 |阅读模式
书目名称New Rapid-acting Antidepressants
编辑Kenji Hashimoto,Mario Manto
视频video
概述Discusses new candidate for rapid-acting antidepressants.Provides information for those who work in the field of CNS drugs.Ideal for pharmacologists, psychiatrists, and those who want to learn about C
丛书名称Contemporary Clinical Neuroscience
图书封面Titlebook: New Rapid-acting Antidepressants;  Kenji Hashimoto,Mario Manto Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive l
描述​This book discusses new candidates for rapid-acting antidepressants, such as (R)-ketamine, (2R,6R)-hydroxynorketamine, scopolamine, mGluR2/3 antagonists and AMPA receptor agonists.  There are serious limitations to currently available antidepressants, such as delayed onset and low rates of efficacy.  The discovery that a single dose of ketamine, an NMDAR antagonist, can produce rapid antidepressant effects that are sustained has led to new research in this area.  In this volume, a variety of novel pharmaceutical treatments are examined.  This volume would be useful to both researchers and clinicians who work in the field of pharmacology, specifically CNS drug treatments..
出版日期Book 2021
关键词Glutamate receptor; NMDA receptor; mGluR receptor; GABA receptor; Muscarinic receptor; IL-6 antibody
版次1
doihttps://doi.org/10.1007/978-3-030-79790-4
isbn_softcover978-3-030-79792-8
isbn_ebook978-3-030-79790-4Series ISSN 2627-535X Series E-ISSN 2627-5341
issn_series 2627-535X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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发表于 2025-3-21 23:25:13 | 显示全部楼层
New Rapid-acting Antidepressants978-3-030-79790-4Series ISSN 2627-535X Series E-ISSN 2627-5341
发表于 2025-3-22 01:57:14 | 显示全部楼层
Kenji Hashimoto,Mario MantoDiscusses new candidate for rapid-acting antidepressants.Provides information for those who work in the field of CNS drugs.Ideal for pharmacologists, psychiatrists, and those who want to learn about C
发表于 2025-3-22 05:55:51 | 显示全部楼层
发表于 2025-3-22 09:04:18 | 显示全部楼层
https://doi.org/10.1007/978-3-030-79790-4Glutamate receptor; NMDA receptor; mGluR receptor; GABA receptor; Muscarinic receptor; IL-6 antibody
发表于 2025-3-22 13:18:19 | 显示全部楼层
(,)-Ketamine: A New Rapid-Acting Antidepressant,ecise molecular and cellular mechanisms underlying the antidepressant effects of (.)-ketamine are unclear, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor activation may have a role in its antidepressant actions. In addition, inflammatory bone markers, extracellular-signal-regulated ki
发表于 2025-3-22 20:11:41 | 显示全部楼层
Novel AMPA Receptor Potentiators TAK-137 and TAK-653 as Potential Rapid-Acting Antidepressants,tivity. In this chapter, I will describe our strategy for discovering AMPA-R potentiators with lower agonistic activity. I will also review the in vitro and in vivo profiles of TAK-137 and TAK-653, including their procognitive and antidepressant-like effects.
发表于 2025-3-22 22:40:42 | 显示全部楼层
AMPA Receptor Potentiators as Potential Rapid-Acting Antidepressants, its behavioral action is blocked by AMPAR antagonists..Moreover, the removal of specific AMPAR subunits from birth results in behavioral and neurochemical characteristics relevant to depression. Taken together, these findings suggest that the stimulation of AMPARs may be a useful approach to treat
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发表于 2025-3-23 07:42:04 | 显示全部楼层
Antidepressant Effects of the Muscarinic Receptor Antagonist Scopolamine: Clinical and Preclinical follow-up investigation of ketamine’s clinical profile. This chapter is an attempt to review the clinical and preclinical antidepressant data of scopolamine with a view on illuminating the critical muscarinic receptor subtype(s) that could prove fruitful as a next-generation antimuscarinic drug targ
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