| 书目名称 | New Molecular Mechanisms of Estrogen Action and Their Impact on Future Perspectives in Estrogen Ther |
| 编辑 | K. S. Korach,A. Hillisch,K. H. Fritzemeier |
| 视频video | |
| 丛书名称 | Ernst Schering Foundation Symposium Proceedings |
| 图书封面 |  |
| 描述 | From our current knowledge, it is obvious that estrogen action in volves more than reproduction and fertility. Rather, estrogens affect and influence a number of other organ systems such as the immune, cardiovascular and central nervous system as well as the gastrointes tinal tract, urinary tract and skeleton. The importance of estrogens and estrogen receptor activity is appreciated from the spectrum of significant physiological dysfunctions that occur when there is a loss The participants of the workshop VI Preface of the hormone or the receptor activity. Loss of estrogen, however (for instance during menopause), occurs with time and results in a variety of clinical conditions. We know that the developmental loss of estrogen, as seen in clinical cases of aromatase gene mutations and experimental models, has dramatic effects in both men and women alike. The evidence that these effects are mediated through the estrogen receptor(s) is based on similar but not always identical phenotypes as observed in experimental animal models of estrogen receptor mutations as well as the single clinical case of an estrogen receptor alpha mutant patient. Developing an understanding of the spectrum |
| 出版日期 | Conference proceedings 2004 |
| 关键词 | Drug Discovery; Estrogen Receptor; Hormone Replacement Therary; Steroid Hormones; Structure Biology; estr |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-662-05386-7 |
| isbn_softcover | 978-3-662-05388-1 |
| isbn_ebook | 978-3-662-05386-7Series ISSN 0947-6075 |
| issn_series | 0947-6075 |
| copyright | Springer-Verlag Berlin Heidelberg 2004 |
发表于 2025-3-21 17:19:43
