Titlebook: New Methods for the Study of Biomolecular Complexes; Werner Ens,Kenneth G. Standing,Igor V. Chernushevi Book 1998 Springer Science+Busines

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Ballerina

Shubhada S. Kulkarni,P. Kristina Taylor,Donald M. Kurtz Jr.,I. Jonathan Amster

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HAWK

Nato Science Series C:http://image.papertrans.cn/n/image/665481.jpg

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滔滔不绝的人

Inelasticity

Observation of Non-Covalent Complexes of Citrate Synthase and NADH by ESI/TOF Mass Spectrometryof the electrospray technique preserves higher order structures, allowing their accurate mass measurement by time-of-flight mass spectrometry over a wide m/z range. Here we demonstrate the application of ESI/TOF MS in the detection of noncovalent complexes and quaternary structural changes as a result of ligand binding to an allosteric enzyme.

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容易生皱纹

A General Approach to Deciphering How Proteins Work Using Synthetic Chemistry and Mass Spectrometrynderstand, for example, how protein domains recognize their target ligands or how enzymes are capable of catalyzing chemical reactions at nearly diffusion limited rates which in some cases are 10.–10. times faster than that of the uncatalyzed reaction. One way to get answers to questions like these