| 书目名称 | New Gold-Catalyzed Reactions and Applications for the Synthesis of Alkaloids |
| 编辑 | Ana Escribano Cuesta |
| 视频video | |
| 概述 | Nominated as an outstanding Ph.D. thesis by the Institute of Chemical Research of Catalonia, ICIQ.A number of important publications in high profile chemistry journals have derived from this work.The |
| 丛书名称 | Springer Theses |
| 图书封面 |  |
| 描述 | Ana Escribano Cuesta‘s thesis presents a detailed study of the inter- and intramolecular reactions of carbonyl compounds with 1,6-enynes using gold (I) complexes. An important part of the work involved streamlining the variables that allow the selective synthesis of different products such as tricyclic compounds, dihydropyrans, 1,3-dienes or cyclobutenes. The second chapter highlights the importance and difficulties in synthesising a cyclobutene subunit and the author includes a detailed description of how the products were prepared. The final chapter outlines the synthesis of lundurines using methodology developed by the author‘s research group for intramolecular gold-catalyzed cyclization of indoles with alkynes. The lundurine products developed in this work show significant in vitro cytoxicity toward B16 melanoma cells. The work in this thesis has led to a number of publications in high-profile chemistry journals. |
| 出版日期 | Book 2013 |
| 关键词 | Antonio M; Echavarren; Cyclization of Alkynylindole; Cyclobutene Compounds; Gold Properties; Gold(I)-Cat |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-00702-1 |
| isbn_softcover | 978-3-319-03385-3 |
| isbn_ebook | 978-3-319-00702-1Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
| issn_series | 2190-5053 |
| copyright | Springer International Publishing Switzerland 2013 |
发表于 2025-3-21 17:20:45
