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Titlebook: New Discoveries on the β-Hydride Elimination; Thomas M. Gøgsig Book 2012 Springer-Verlag Berlin Heidelberg 2012 Carbonylative Heck Reactio

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书目名称New Discoveries on the β-Hydride Elimination
编辑Thomas M. Gøgsig
视频video
概述Nominated by Aarhus University as an outstanding PhD dissertation.Describes new discoveries on the ß-hydride elimination and on transition metal catalysis that will help to improve the outcome of the
丛书名称Springer Theses
图书封面Titlebook: New Discoveries on the β-Hydride Elimination;  Thomas M. Gøgsig Book 2012 Springer-Verlag Berlin Heidelberg 2012 Carbonylative Heck Reactio
描述The work presented in Thomas M. Gøgsig‘s thesis deals with the discovery of new metal-catalyzed transformations ranging from Kumada-, Heck- and Suzuki-type reactions. The thesis starts with a formidable introduction to Pd-catalyzed cross-coupling reactions. New results have been obtained on: .(i) Pd-catalyzed 1,2-migration reactions, .(ii) Pd-catalyzed Heck reactions employing heteroaromatic tosylates, .(iii) Ni-catalyzed Heck reactions, and .(iv) Pd-catalyzed carbonylative Heck reaction. .Metal-catalyzed cross-coupling reactions are today a highly competititve field (the 2010 Nobel Prize in Chemistry was awarded "for palladium-catalyzed cross couplings in organic synthesis", the 2001 and 2005 Nobel Prizes in closely related fields). Thomas M. Gøgsig obtained new results in his thesis that will help to improve the outcome of catalytic processes and improve their scope. The results will thus become key references for tomorrow‘s new applications. All chapters include insightful discussions and in-depth descriptions of the key principles of these new discoveries.
出版日期Book 2012
关键词Carbonylative Heck Reaction; Cross-coupling Reactions; Heck Reaction; Kumada Coupling; Negishi Coupling;
版次1
doihttps://doi.org/10.1007/978-3-642-32099-6
isbn_softcover978-3-662-52264-6
isbn_ebook978-3-642-32099-6Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer-Verlag Berlin Heidelberg 2012
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Heteroaromatic Tosylates in the Regioselective Heck Reaction,n of the crucial cationic palladium(II) complex is readily formed after the oxidative addition due to the weak coordinating abilities of the triflate anion. The employment of other sulfonate derivatives such as aryl tosylates in the Heck reaction, representing a more stable and less costly alternati
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Conclusions,palladium catalysis has established its position as one of the most powerful and reliable strategies in the syntheses of a broad spectrum of pharmaceuticals, agrochemicals, cosmetics etc. In order to develop this area of organometallic chemistry even further a full understanding of the involved mech
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