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Titlebook: New Developments in Lipid-Protein Interactions and Receptor Function; K. W. A. Wirtz,L. Packer,J. P. Changeux Book 1993 Springer Science+B

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书目名称New Developments in Lipid-Protein Interactions and Receptor Function
编辑K. W. A. Wirtz,L. Packer,J. P. Changeux
视频video
丛书名称NATO Science Series A:
图书封面Titlebook: New Developments in Lipid-Protein Interactions and Receptor Function;  K. W. A. Wirtz,L. Packer,J. P. Changeux Book 1993 Springer Science+B
描述A NATO Advanced Study Institute on "New Developments in Lipid-Protein Interactions and Receptor Function" was held on the Island of Spetsai, Greece, from August 16-27, 1992. This Institute was organized to bring together researchers in the field of membrane organization and dynamics with those actively involved in studies on receptor function, signal transduction mechanisms and gene regulation. 2 Presentations and discussions focussed on the regulation of intracellular Ca +-levels, on the second messengers derived from inositol lipids and on the specific phospholipase C isozymes involved in these processes. A major focus was on G-proteins and the effect of lipid anchors on their function. These principles of regulation were further discussed in the context of receptors for acetylcholine, lysophosphatidic acid and low-density lipoproteins. In addition, various aspects of the genomic regulation of cell growth and differentiation by transcription factors were presented. These topics were put into perspective by discussing the most recent developments in lipid-protein interactions, protein insertion into membranes, membrane lipid organization and lipid dynamics as mediated by phospholi
出版日期Book 1993
关键词Lipid; Oxidation; biosynthesis; cell growth; genes; proteins; signal transduction; transcription
版次1
doihttps://doi.org/10.1007/978-1-4615-2860-9
isbn_softcover978-1-4613-6239-5
isbn_ebook978-1-4615-2860-9
copyrightSpringer Science+Business Media New York 1993
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Transcription Factor Crem: A Key Element of the Nuclear Response to cAMPaltering the spectrum of genes expressed, the cell appropriately modifies its physiology for a given stimulus. Aberrations in this process can lead to deregulated cell proliferation and ultimately tumorigenesis.
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Recognition of Precursor Proteins by the Mitochondrial Protein Import Apparatusosymbionts in the ancestor of the eukaryotic cell (Margulis, 1970; Schwartz and Dayhoff, 1978). A large number of the original prokaryotic features are retained in the organelles. In the course of evolution, both organelles have lost most of their genetic information, which has been transferred to the nucleus (Schwartz and Dayhoff, 1978).
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Greece, from August 16-27, 1992. This Institute was organized to bring together researchers in the field of membrane organization and dynamics with those actively involved in studies on receptor function, signal transduction mechanisms and gene regulation. 2 Presentations and discussions focussed o
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Tumor Necrosis Factor Cytotoxicity is Associated with Activation of Cellular Phospholipasesd cells is often much more pronounced in combination with synergizing agents [e.g. interferon-γ (Williamson et al., 1983), LiC1 (Beyaert et al., 1989)], making this molecule a good candidate for future cancer therapy development.
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Regulation of Gene Expression in Rodent Hepatocytesct with them and control the transcription of several other genes (Blau, 1988). Thus a cascade of molecular interactions is initiated that will ultimately lead to the adult phenotype. Additional regulatory mechanisms are then required for the maintenance of the differentiated state.
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