Titlebook: New Concepts in Viral Heart Disease; Virology, Immunology Heinz-Peter Schultheiß Conference proceedings 1988 Springer-Verlag Berlin Heidelb

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Induction of Soluble Mediators During Coxsackievirus B3 Replication In Vitro and In Vivordium [7, 9, 18, 41–43]. Within hours of virus inoculation, virus appears in the blood [24] and remains in the plasma phase over the next 2–3 days [1, 8]. Virus is also associated with circulating leukocytes [6, 13]. During this period, virus enters the myocardium and replicates in unidentified cell

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Persistence of Echovirus Type 6 in Cultured Cellsand cause self-limiting infections, the enteroviruses can also establish persistent infections which result in chronic disease syndromes [3, 7, 9, 11, 14, 17–19]. Recent experiments by Kandolf [7] suggest that chronic dilated cardiomyopathies are associated with persistence of a variety of different

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Detection and Typing of Enteroviruses by Nucleic Acid Probes and Monoclonal Antibodies strain. One of the problems in this method is the long time period needed for final diagnosis. In addition some coxsackievirus (CV) type A (CVA) strains can only be isolated in newborn mice. Gene technology and hybridoma methods offer new possibilities for development of reagents which can be used

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Virus-Induced Autoimmunity: Cross-Reactivity of Antiviral Antibodies with Self-Componentsth autoantibodies present against a number of tissues and organs. For example, in systemic lupus erythematosus, autoantibodies against DNA, RNA, cytoplasmic proteins, lymphocytes, and erythrocytes are often found. Similarly, patients with polyendocrinopathy have autoantibodies to pancreas, thyroid,

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Induction of Soluble Mediators During Coxsackievirus B3 Replication In Vitro and In Vivong the 4–10 day (p. i.) period were cells producing viral antigens [11] or viral RNA (N. M. Chapman, S. M. Tracy, and C. J. Gauntt, unpublished data) detected in nascent or developing lesions. The data suggest that virus infection of a cell (or cells) in the myocardium initiates a series of events t

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