Titlebook: New Concepts in Cancer; Metastasis, Oncogene C. Etievant,J. Cros,Y. M. Rustum Textbook 1990Latest edition Macmillan Publishers Limited 1990

abysmal

grovel

Instinctive

暗讽

Cell Growth Signaling in Fibroblasts: the Role of G-Proteins,uding cultured fibroblasts, smooth muscle cells and epithelial cells, it is possible to define key stages of the cell cycle where growth-promoting agents exert their action, and to delineate signaling pathways involved in initiation, progression or arrest of cell growth.

隐藏

Textbook 1990Latest editionactors associated with and/or responsible for tumor metastasis and evaluates the role of various growth factors in metastasis and therapy. It also considers the possible relationship between the overexpression of oncogenes and clinical resistance to chemotherapy and possible therapeutic strategies a

创造性

Organ Specificity of Metastasis: Adhesive, Invasive and Growth Properties of Organ-Specific Metastametastasis can occur to selective secondary sites that would be unexpected on the basis of mechanical considerations or circulatory or lymphatic patterns (Table 3.1) (Sugarbaker, 1981; Nicolson, 1982a, 1988a, b).

archetype

The Control of Cell Movement by Laminin, and its Role in Metastasis,shape. Not surprisingly, this molecule has been found implicated in biological situations which imply cell migration, tissue remodeling and phenotype fluctuation, such as embryogenesis (Ekblom ., 1980; Sanes, 1985) or malignancy. On the basis of our experience we review the main factors in laminin control of cell movement.

exercise

Estrogen-induced Pro-cathepsin D and its Relationship to Breast Cancer Invasion and Metastasis,invasion have been identified and used to develop antibodies allowing direct studies in mammary tumor biopsies. One fruitful approach to identifying such factors has been to detect the proteins, enzymes, and factors secreted in conditioned media by estrogen-receptor-(RE)-positive breast cancer cells following their stimulation by estrogens.

出处

patella

New Therapeutic Approaches in Recurrent Metastatic Disease,nt foci of metastatic tumor cells in different locations. Until very recently the appearance of metastases meant a high probability of death. Although there is no single clinically useful agent that could be defined as a specific antimetastatic drug, advances have been made in the treatment of some metastatic cancers during the last decade.