Titlebook: New Bioprocessing Strategies: Development and Manufacturing of Recombinant Antibodies and Proteins; Bob Kiss,Uwe Gottschalk,Michael Pohlsc

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Michael Pohlscheidt,Robert Kiss,Uwe Gottschalk-level regression, are detailed in Appendix A. This book will be valuable in graduate courses on applied regression, as well as for practitioners and researchers in the fields of data science, statistical analytics, public health, and related fields..

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Eytan Abraham,Behnam Baghbaderani Ahmadian,Kathryn Holderness,Yonatan Levinson,Erika McAfee of evidence. An example from the published literature will be given that illustrates how the conventional comparison of a p-value to the conventional cutoff 0.05 may be misleading and harmful. The problem of dealing with false positive conclusions in multiple testing will be discussed. Type S error

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Barb Thorne,Ryan Takeya,Francesca Vitelli,Xin Swanson The final example shows what can go wrong when one ignores fundamental experimental design issues, including bias and confounding, when evaluating and comparing multiple treatments. As an alternative approach, the family of randomized select-and-test designs will be presented.

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A Different Perspective: How Much Innovation Is Really Needed for Monoclonal Antibody Production Usicacy also builds on the established commercial history of recombinant antibodies, which dates back to 1997..Efforts to increase titers further will likely yield diminishing returns. Very few products would benefit significantly from a titer greater than 8 g/L; in many cases, a downstream processing

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0724-6145 guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.978-3-319-97110-0Series ISSN 0724-6145 Series E-ISSN 1616-8542