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Titlebook: New Avenues to Efficient Chemical Synthesis; Emerging Technologie P.H. Seeberger,T. Blume Conference proceedings 2007 Springer-Verlag Berli

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书目名称New Avenues to Efficient Chemical Synthesis
副标题Emerging Technologie
编辑P.H. Seeberger,T. Blume
视频video
概述Compact overview of the current status of the respective technologies in synthesis.Includes many "real life" examples from industry and academic institutions
丛书名称Ernst Schering Foundation Symposium Proceedings
图书封面Titlebook: New Avenues to Efficient Chemical Synthesis; Emerging Technologie P.H. Seeberger,T. Blume Conference proceedings 2007 Springer-Verlag Berli
描述.In modern drug discovery and development, chemical synthesis is one of the key technologies. For the rapid preparation of new test compounds and drug development candidates, several innovative technologies with great potential have emerged: Microreactor chemistry; Nanotechnology and catalysis research; Microwave-assisted organic synthesis; New developments in solid supported synthesis...This book covers lectures about the theory, use, scope and limitations of these new technologies in chemical synthesis. It provides a useful overview for scientists in the pharmaceutical industry as well as in academic institutions interested in chemical synthesis for drug discovery and development..
出版日期Conference proceedings 2007
关键词Chemical Synthesis; Medicinal Chemistry; New Technologies; catalysis; chemistry; nanotechnology; organic c
版次1
doihttps://doi.org/10.1007/978-3-540-70849-0
isbn_softcover978-3-642-42084-9
isbn_ebook978-3-540-70849-0Series ISSN 0947-6075
issn_series 0947-6075
copyrightSpringer-Verlag Berlin Heidelberg 2007
The information of publication is updating

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Micro-Fluidic and Lab-on-a-Chip Technology,e, but also access a range of unique characteristics, which are not achievable in conventional macro-scale systems. This chapter will discuss the unique properties of miniaturised systems based on micro-fluidic and Lab-on-a-Chip technology and consider how these may influence the overall performance
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Microreactors as New Tools for Drug Discovery and Development,me than is achievable with large-scale batch reactors. With monitoring of output flow, microreactors can be adjusted exquisitely to give enhanced and inherently safer protocols. Bulk production can be achieved through long run times or parallel reactors. However, microreactors can also be used advan
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Microchemical Systems for Discovery and Development,iphase catalytic systems to microsystems for multistep chemical synthesis. The latter systems involve extraction and gas–liquid separation processes designed to take advantage of the dominance of surface tension effects in microfluidic devices. Integration of physical sensors (e.g., for pressure, te
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An Integrated Approach to Developing Chemoenzymatic Processes at the Industrial Scale,protein expression, high-throughput screening, and enzyme evolution technologies. To truly impact chemical synthesis at the industrial scale, biotransformations and chemical research and development must be integrated to develop cost-effective and environmentally friendly solutions for drug manufact
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Solid-Phase Supported Synthesis: A Possibility for Rapid Scale-Up of Chemical Reactions,ed hydroxamic acid derivative as examples. These compounds were obtained through combinatorial chemistry and solution-phase synthesis was used in parallel to provide a comparison. By applying highly loaded polystyrene-derived resins as the solid support, a good ratio between the product and the star
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