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Titlebook: New Approaches in Cancer Pharmacology: Drug Design and Development; Vol. II Paul Workman (Chairman),Maurizio D’lncalci (Co-Cha Conference p

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Discovery of Improved Platinum Analogues, remained unknown until the work of Barnett Rosenberg, some 125 years later. Rosenberg attributed the toxic effects of an alternating electric field applied to a suspension of . to the generation of .-dichlorodi-ammine platinum II (cisplatin). Subsequently, cisplatin was shown to possess potent acti
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Discovery and Design of Inhibitors of Oncogenic Tyrosine Kinases,cremental value against the major solid tumours will require a radically different strategy. Rather than the “black box” approach of random screening for cytotoxicity or cytostasis, or even the rational design of improved agents acting on conventional drug targets [1,2], many believe that this quant
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