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Titlebook: Neuronal-glial Cell Interrelationships; Report of the Dahlem T. A. Sears Conference proceedings 1982 Dr. S. Bernhard, Dahlem Konferenzen, B

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stigator, a statement which I must now qualify lest it be taken as a faint-hearted view of the problems which confront us in this or any other field of disease-orientated re­ search. In recent years the growth and scope of MS research parallels, in fact reflects, that which has occurred more general
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The Development of Electrical Excitability excitability develops in both old and new membrane; development of excitability in the newly-formed membrane may recapitulate earlier embryonic development. The role of excitability in development remains enigmatic; the available experimental evidence suggests that the Na. action potential plays little or no role in early neural development.
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Cell Interactions and the Cytoskeleton known. Recent studies of the cytoskeleton itself, concentrating on in situ analysis, have provided new approaches to this problem. They have altered our view of cytoskeletal organization and expanded the possible functions of the transmembrane connection.
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Mechanism of Viral Injury to the Nervous System elements and/or alteration of their function, establishment of persistent infections, and virally directed immune damage to the nervous system. The molecular basis for some of these processes are now beginning to be elucidated.
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Stephen W. Kuffler (1913–1980)etch receptors and muscle spindles, efferent control, pre- and postsynaptic inhibition, GABA and peptides as transmitters, integration in the retina, and the detailed analysis of synaptic transmission.
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Maintenance State of the Art Reportessing up to whole cells. One of its chief values will probably be in mapping some of the vast gaps in our knowledge of these normal interactions, and in pointing out areas ready for fruitful investigation.
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Distribution and Functional Significance of Sodium and Potassium Channels in Normal and Acutely Demyional specialization of the mammalian fiber for rapid passage of impulses (high sodium channel density and low potassium channel density at the node) may require some stabilizing influence in the paranodal region to prevent re-entrant type phenomena (hence the internodal potassium channels).
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