Titlebook: Neuroinflammation — From Bench to Bedside; H. Kettenmann,G. A. Burton,U. J. Moenning Conference proceedings 2002 Springer-Verlag Berlin He

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Neuronal SLC (CCL21) Expression: Implications for the Neuron-Microglial Signaling System,more than 70% of the cell population of the CNS and consist of three different cell types: astrocytes, oligodendrocytes, and microglia. Particularly, astrocytes and microglia are considered as the neuroimmune cells in the CNS. The microglial cell, originally described by del Rio-Hortega (1932), has

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Cytokine-Mediated Inflammation and Other Actions in the Central Nervous System, of functions necessary for tissue and host protection and recovery. In particular, these molecules are pivotal in the regulation of inflammatory processes. In normal physiologic states, the level of various cytokines in the CNS is tightly controlled and very low to undetectable. However, increased

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,Activated Microglia in Alzheimer’s Disease and Stroke,ltiple sclerosis. Increasing evidence points to a role for microglia in the inflammatory cascades in Alzheimer’s disease and stroke. In particular, microglial activation is apparent (Haga et al.1989; Altsteil and Sperber 1991; Morioka et al. 1991; Munoz 1991; Aisen 1997; Rupalla et al. 1998; Yrjänhe

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,Inflammation in Stroke — A Potential Target for Neuroprotection?,rs, clinicians and researchers alike have been disappointed by the outcome of clinical trials aimed at decreasing damage after cerebral ischemia. Currently, only thrombolytic therapy initiated within a narrow time frame of hours after the onset of ischemia has become an accepted therapeutic option (

联想

,Neuroinflammation in Alzheimer’s Disease: Potential Targets for Disease-Modifying Drugs,d the alterations in neuronal and glial morphology have been consistently detected in the brains of demented patients. During the following decades with the enormous developments in molecular biology and electron microscopy, the most obvious histopathological elements of AD have been described in mo

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Chemokine Receptors on Mononuclear Phagocytes in the Central Nervous System of Patients with Multipscade of multiple sclerosis (MS), which frequently culminates in irreversible injury to myelin and axons (Sørensen and Ransohoff 1998). Although MS pathology is heterogeneous among patients (Lucchinetti et al. 2000), it still remains clear that destruction of myelin and axons as well as oligodendroc

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The Role of Apoptosis in Neuroinflammation,rocesses determine the outcome in, for example, brain injury (Woiciechowsky et al. 1998) and cerebral ischemia (Dirnagl et al. 1999). The classical and most demanding acute inflammatory disease of the CNS is bacterial meningitis which still displays a mortality rate of about 20%, despite effective a

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die Fertigbauweise und den Leimbau neue An­ wendungsgebiete erschlossen, bei denen man sich um sparsamere Bemessung be­ müht. Sein günstiges Verhältnis von Zugfestigkeit zu Rohdichte, die Reißlänge*, läßt Holz für viele Anwendungen im Leichtbau geeignet erscheinen. Wo Holz in handwerklicher Überlie