Titlebook: Neuroinflammation and Schizophrenia; Golam M. Khandaker,Urs Meyer,Peter B. Jones Book 2020 Springer Nature Switzerland AG 2020 inflammatio

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From Infection to the Microbiome: An Evolving Role of Microbes in Schizophrenia, This intersection of disciplines, however, has a rich history and is currently revitalized by newfound functions of the microbiome and the gut-brain axis in human diseases. Schizophrenia, in particular, fits this model as a disorder with gene and environmental roots that may be anchored in the immu

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Herpes Simplex Virus Type-1 Infection: Associations with Inflammation and Cognitive Aging in Relati likely to be due to multiple causes. Persistent or repeated infections of the central nervous system (whether subclinical or diagnosable) can cause damage to neurons directly or indirectly through inflammation resulting in incremental neuronal damage, thus eroding cognitive reserve. This possibilit

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Role of Infection, Autoimmunity, Atopic Disorders, and the Immune System in Schizophrenia: Evidence autoimmune diseases could be involved in the pathogenesis of schizophrenia. Psychotic symptoms can be directly triggered by infections reaching the CNS, or be secondary to systemic inflammation indirectly affecting the brain through immune components, such as brain-reactive antibodies and cytokines

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Early-Life Adversity, Systemic Inflammation and Comorbid Physical and Psychiatric Illnesses of Adulpsychosis. However, what is causing this increased immune activation and how this leads to the development of psychopathology remain still unclear. In this chapter we discuss the evidence about the role of childhood trauma as possible underlying cause of the increased immune activation in patients w

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Inflammation, Antipsychotic Drugs, and Evidence for Effectiveness of Anti-inflammatory Agents in Scnt evidence points to various immunological abnormalities in schizophrenia, including cell-mediated processes, acute phase proteins, cytokines, and intracellular mediators. Trait- and state-related immune dysfunction appears to exist, and a strong case can therefore be made for immunomodulation ther

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https://doi.org/10.1007/978-3-030-39141-6inflammation; immune system; schizophrenia; psychotic disorders; animal models; clinical studies