Titlebook: Neuroimmune Interactions in Pain; Mechanisms and Thera Ru-Rong Ji,Jianguo Cheng,Jasmine Ji Book 2023 The Editor(s) (if applicable) and The

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Inflammation and Pain,ss, heat, swelling, loss of function, and pain. Because of its relationship with pain and injury, various treatments for inflammation have been historically documented. During inflammation, pro-inflammatory mediators can be produced by infiltrating and resident immune cells. These pro-inflammatory m

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Animal Models of Pain and Anti-inflammatory Treatments,findings that appear promising in animals fail to translate to human disease, underscoring the criticality of thoughtful model establishment and meaningful behavioral testing. In this chapter, we review current methods for the measurements of mechanical pain, thermal pain, and spontaneous pain in mi

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Sex Differences in Pain with Emphasis on Neuroimmune Interactions,m chronic pain at greater rates than men, the current mechanistic understanding of chronic pain has been predominantly derived from the study of male animals. As such, a greater emphasis will be needed to investigate female-specific signaling mechanisms in chronic pain. These efforts will improve ou

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Neuroimmune Interactions in Acute and Chronic Itch,eral nervous systems engage in extensive interactions termed “crosstalk,” which gives rise to both acute and chronic itch pathologies. Peripheral sensory neurons detect itch-triggering stimuli from the environment to transduce pruritic signals. Itch signals travel from nerve fibers in the skin and p

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