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Titlebook: Neuroendocrine Tumours; Diagnosis and Manage Suayib Yalcin,Kjell Öberg Book 20151st edition The Editor(s) (if applicable) and The Author(s)

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Molecular Biology of Neuroendocrine Tumors,ever, cure of advanced NET disease remains elusive. Further progress in our understanding of the molecular mechanisms involved in NET carcinogenesis and the introduction of novel biology-based effective treatments into clinical practice will open new horizons for planning tailored surgical or medica
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Circulating Biomarkers in Neuroendocrine Tumours,erial to precisely delineate their role. There is still an unmet need for new sensitive markers for early detection and screening for NETs, but the most recent work on whole-genome sequencing might come up with new potential both circulating and tissue markers.
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Overview of Gastrointestinal Neuroendocrine Tumours,ications. Primary duodenal NETs account for less than 2 % of all gastrointestinal NETs. They are relatively benign lesions with slow growth pattern and low metastatic potential. The ileum and appendix are the most common sites of NETs in the West, while colorectal NETs are relatively more common in
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Nonfunctioning Pancreatic Neuroendocrine Tumors,ed chemotherapy was approved in the 1970s. Over the last decade, several molecular-targeted agents and novel chemotherapeutics have been developed. In 2011, everolimus, a mammalian target of rapamycin inhibitor, and sunitinib, a multitargeted inhibitor, were approved for progressing well-/moderately
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Introduction to Neuroendocrine Tumours,ave been adapted and guidelines published to help to establish a more standardised approach. The estimated incidence of 5.25/100,000 in 2004 is expected to reach to 8/100,000. Although NETs may occur at any age, it is more common after the age of 50. NETs may be associated with familial genetic neur
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