Titlebook: Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances; Aejaz Nasir,Domenico Coppola Book 2016 Springer Science+Bu

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Neuroendocrine Tumors (NETs) of the Mediastinum and Thymusdge the existence of carcinoid tumors in the thymus and to separate them from more common tumors arising in this location, such as thymoma. The source of the primary NETs of the thymus has been proposed that they are derived from Kulchitsky cells. In this chapter we discussed the World Health Organi

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Neuroendocrine Tumors of the Esophagus esophageal NETs are classified under foregut neuroendocrine neoplasm (NENs) category, and their grading and staging follows the general rule as for foregut NETs of elsewhere. Several genetic and epigenetic alterations and molecular pathway dysregulations have been proposed to be involved in the pat

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Neuroendocrine Neoplasms of the Pancreasger age group than pancreatic ductal adenocarcinomas. Traditionally, PanNETs have been classified according to their hormone secretory status as either functional or nonfunctional based on whether they produce a clinically recognizable syndrome due to hormone secretion. The majority of PanNETs today

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Neuroendocrine Neoplasms of the Small Intestinetegorized under the midgut neuroendocrine neoplasm (NENs) category. Midgut NETs are the most common type of neuroendocrine neoplasm. Although SI-NENs are rare, in general, they are the most common malignancy of the small bowel and about half of all small intestine neoplasms have neuroendocrine origi

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Adrenal Neuroendocrine Tumors: Pheochromocytoma and Neuroblastic Tumorsce catecholamines. Pheochromocytomas are tumors arising from the chromaffin cells within the adrenal gland. These tumors are termed paraganglioma if arising from chromaffin cells outside of the adrenal. In embryonic development, sympathecoblasts form clusters which during embryogenesis can remain in